This review article discusses the gut microbiota and vitamin D as an emerging and vital axis influencing immune aging and age-related diseases. It highlights the dual role of gut microbiota in shaping host immunity and regulating vitamin D metabolism, alongside the significant immunomodulatory potential of vitamin D in maintaining intestinal homeostasis and barrier integrity. The findings suggest that vitamin D deficiency and gut dysbiosis accelerate immunosenescence and inflammageing, contributing to unhealthy aging and increased risk of age-related diseases.
Gut
Gut-vitamin D interplay: key to mitigating immunosenescence and promoting healthy ageing
Immunity & Ageing
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Skin Exposure to Narrow Band Ultraviolet (UVB) Light Modulates the Human Intestinal Microbiome
Frontiers in Microbiology
This study shows that treatment with narrowband UVB light therapy leads to changes in the gut microbiome including increases to microbiota diversity, suggesting a novel skin-gut axis for promoting gut health.
Gut
Skin Exposure to Narrow Band Ultraviolet (UVB) Light Modulates the Human Intestinal Microbiome
Frontiers in Microbiology
This study shows that treatment with narrowband UVB light therapy leads to changes in the gut microbiome including increases to microbiota diversity, suggesting a novel skin-gut axis for promoting gut health.
Gut
The gut-skin axis: a bi-directional, microbiota-driven relationship with therapeutic potential
Gut Microbes
This review explores the gut-skin axis, describing the interaction that occurs between the skin and the gastrointestinal tract. Recent studies show that exposing the skin to ultraviolet B-light can beneficially modulate both the gut microbiome and intestinal health.
Gut
The gut-skin axis: a bi-directional, microbiota-driven relationship with therapeutic potential
Gut Microbes
This review explores the gut-skin axis, describing the interaction that occurs between the skin and the gastrointestinal tract. Recent studies show that exposing the skin to ultraviolet B-light can beneficially modulate both the gut microbiome and intestinal health.
Gut
Effect of Vitamin D Supplementation on Human Gut Microbiota: A Systematic Review of Randomized Controlled Trials
Nutrition Reviews
This review article looked at 14 RCTs investigating the impact of vitamin D supplementation (dose ranging from 1680-7000 IU/day) on gut microbiota. They found that vitamin D supplementation modulates gut microbiota composition, with significant increase observed in bacterial taxa associated with anti-inflammatory and gut health-promoting properties, such as Bifidobacterium and Lactobacillus as well as increase in Bacteroides and Firmicutes ratio. Some trials also reported enhanced microbial diversity (α and β diversity).
Gut
Effect of Vitamin D Supplementation on Human Gut Microbiota: A Systematic Review of Randomized Controlled Trials
Nutrition Reviews
This review article looked at 14 RCTs investigating the impact of vitamin D supplementation (dose ranging from 1680-7000 IU/day) on gut microbiota. They found that vitamin D supplementation modulates gut microbiota composition, with significant increase observed in bacterial taxa associated with anti-inflammatory and gut health-promoting properties, such as Bifidobacterium and Lactobacillus as well as increase in Bacteroides and Firmicutes ratio. Some trials also reported enhanced microbial diversity (α and β diversity).