This meta-analysis of 34 observational studies that followed 180,667 participants showed that baseline serum 25(OH)D levels were inversely associated with total number of cardiovascular disease (CVD) events (including myocardial infarction, ischemic heart disease, heart failure, and stroke) and mortality risk. Overall, the risk of CVD events was 10% lower for each 10 ng/mL increase in serum 25(OH)D.
Heart
Serum 25-hydroxyvitamin D and the risk of cardiovascular disease: dose-response meta-analysis of prospective studies
The American Journal of Clinical Nutrition
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25-Hydroxyvitamin D Levels and Risk of Ischemic Heart Disease, Myocardial Infarction, and Early Death
Arteriosclerosis, Thrombosis, and Vascular Biology - American Heart Association Journals
This population-based study and meta-analysis found increasing risk of ischemic heart disease, myocardial infarction, and early death with decreasing vitamin D levels. In comparing individuals in the lowest versus highest vitamin D percentiles, risk was increased by 40% for ischemic heart disease, by 64% for myocardial infarction, by 57% for early death, and by 81% for fatal ischemic heart disease/myocardial infarction.
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25-Hydroxyvitamin D Levels and Risk of Ischemic Heart Disease, Myocardial Infarction, and Early Death
Arteriosclerosis, Thrombosis, and Vascular Biology - American Heart Association Journals
This population-based study and meta-analysis found increasing risk of ischemic heart disease, myocardial infarction, and early death with decreasing vitamin D levels. In comparing individuals in the lowest versus highest vitamin D percentiles, risk was increased by 40% for ischemic heart disease, by 64% for myocardial infarction, by 57% for early death, and by 81% for fatal ischemic heart disease/myocardial infarction.
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Low sun exposure habits is associated with a dose‑dependent increased risk of hypertension: a report from the large MISS cohort
Photochemical & Photobiological Sciences
This observational study involving 23,593 women found that sun exposure was associated with a dose-dependent reduced risk of hypertension, which might partly explain the fewer deaths of cardiovascular disease with increasing sun exposure. As compared to those women with the greatest sun exposure, women with low and moderate sun exposure were at 41% and 15% higher odds of hypertension.
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Low sun exposure habits is associated with a dose‑dependent increased risk of hypertension: a report from the large MISS cohort
Photochemical & Photobiological Sciences
This observational study involving 23,593 women found that sun exposure was associated with a dose-dependent reduced risk of hypertension, which might partly explain the fewer deaths of cardiovascular disease with increasing sun exposure. As compared to those women with the greatest sun exposure, women with low and moderate sun exposure were at 41% and 15% higher odds of hypertension.
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Impact of ultraviolet radiation on cardiovascular and metabolic disorders: The role of nitric oxide and vitamin D
Photodermatology, Photoimmunology & Photomedicine
UVB exposure can influence cardiovascular and metabolic health through nitric oxide (NO)–mediated pathways that do not require vitamin D synthesis.This review summarizes the systemic effects of UV radiation on hypertension and several metabolic diseases such as obesity and diabetes. UVB stimulates NO production in the skin, which enters circulation to promote vasodilation, lower blood pressure, and reduce cardiovascular risk.
Heart
Impact of ultraviolet radiation on cardiovascular and metabolic disorders: The role of nitric oxide and vitamin D
Photodermatology, Photoimmunology & Photomedicine
UVB exposure can influence cardiovascular and metabolic health through nitric oxide (NO)–mediated pathways that do not require vitamin D synthesis.This review summarizes the systemic effects of UV radiation on hypertension and several metabolic diseases such as obesity and diabetes. UVB stimulates NO production in the skin, which enters circulation to promote vasodilation, lower blood pressure, and reduce cardiovascular risk.