This narrative review summarizes the different strands of data linking vitamin D and inflammatory bowel disease (IBD), whilst also outlining the possible beneficial effects of vitamin D supplementation in managing IBD in humans. Low serum levels of the major circulating form of vitamin D, 25-hydroxyvitamin D (25-OH-D) are significantly more prevalent in patients with IBD, particularly in the winter and spring months when UV-induced synthesis of vitamin D is lower. Dietary malabsorption of vitamin D may also contribute to low serum 25(OH)D in IBD.
Gut
The Role of Vitamin D in Inflammatory Bowel Disease: Mechanism to Management
Nutrients
Related Studies
Gut
Skin Exposure to Narrow Band Ultraviolet (UVB) Light Modulates the Human Intestinal Microbiome
Frontiers in Microbiology
This study shows that treatment with narrowband UVB light therapy leads to changes in the gut microbiome including increases to microbiota diversity, suggesting a novel skin-gut axis for promoting gut health.
Gut
Skin Exposure to Narrow Band Ultraviolet (UVB) Light Modulates the Human Intestinal Microbiome
Frontiers in Microbiology
This study shows that treatment with narrowband UVB light therapy leads to changes in the gut microbiome including increases to microbiota diversity, suggesting a novel skin-gut axis for promoting gut health.
Gut
The gut-skin axis: a bi-directional, microbiota-driven relationship with therapeutic potential
Gut Microbes
This review explores the gut-skin axis, describing the interaction that occurs between the skin and the gastrointestinal tract. Recent studies show that exposing the skin to ultraviolet B-light can beneficially modulate both the gut microbiome and intestinal health.
Gut
The gut-skin axis: a bi-directional, microbiota-driven relationship with therapeutic potential
Gut Microbes
This review explores the gut-skin axis, describing the interaction that occurs between the skin and the gastrointestinal tract. Recent studies show that exposing the skin to ultraviolet B-light can beneficially modulate both the gut microbiome and intestinal health.
Gut
Effect of Vitamin D Supplementation on Human Gut Microbiota: A Systematic Review of Randomized Controlled Trials
Nutrition Reviews
This review article looked at 14 RCTs investigating the impact of vitamin D supplementation (dose ranging from 1680-7000 IU/day) on gut microbiota. They found that vitamin D supplementation modulates gut microbiota composition, with significant increase observed in bacterial taxa associated with anti-inflammatory and gut health-promoting properties, such as Bifidobacterium and Lactobacillus as well as increase in Bacteroides and Firmicutes ratio. Some trials also reported enhanced microbial diversity (α and β diversity).
Gut
Effect of Vitamin D Supplementation on Human Gut Microbiota: A Systematic Review of Randomized Controlled Trials
Nutrition Reviews
This review article looked at 14 RCTs investigating the impact of vitamin D supplementation (dose ranging from 1680-7000 IU/day) on gut microbiota. They found that vitamin D supplementation modulates gut microbiota composition, with significant increase observed in bacterial taxa associated with anti-inflammatory and gut health-promoting properties, such as Bifidobacterium and Lactobacillus as well as increase in Bacteroides and Firmicutes ratio. Some trials also reported enhanced microbial diversity (α and β diversity).