A study of 1739 participants found that in those with hypertension, rate of cardiovascular disease was approximately twice as high in those with vitamin D levels less than 15 ng/mL as in those with vitamin D levels greater than 15 ng/mL. Exploratory analyses suggested a nonlinear relation between vitamin D levels and cardiovascular risk, with increased hazard for cardiovascular events at vitamin D levels below 15 to 20 ng/mL.
Heart
Vitamin D Deficiency and Risk of Cardiovascular Disease
Circulation
Related Studies
Heart
25-Hydroxyvitamin D Levels and Risk of Ischemic Heart Disease, Myocardial Infarction, and Early Death
Arteriosclerosis, Thrombosis, and Vascular Biology - American Heart Association Journals
This population-based study and meta-analysis found increasing risk of ischemic heart disease, myocardial infarction, and early death with decreasing vitamin D levels. In comparing individuals in the lowest versus highest vitamin D percentiles, risk was increased by 40% for ischemic heart disease, by 64% for myocardial infarction, by 57% for early death, and by 81% for fatal ischemic heart disease/myocardial infarction.
Heart
25-Hydroxyvitamin D Levels and Risk of Ischemic Heart Disease, Myocardial Infarction, and Early Death
Arteriosclerosis, Thrombosis, and Vascular Biology - American Heart Association Journals
This population-based study and meta-analysis found increasing risk of ischemic heart disease, myocardial infarction, and early death with decreasing vitamin D levels. In comparing individuals in the lowest versus highest vitamin D percentiles, risk was increased by 40% for ischemic heart disease, by 64% for myocardial infarction, by 57% for early death, and by 81% for fatal ischemic heart disease/myocardial infarction.
Heart
Serum 25-hydroxyvitamin D and the risk of cardiovascular disease: dose-response meta-analysis of prospective studies
The American Journal of Clinical Nutrition
This meta-analysis of 34 observational studies that followed 180,667 participants showed that baseline serum 25(OH)D levels were inversely associated with total number of cardiovascular disease (CVD) events (including myocardial infarction, ischemic heart disease, heart failure, and stroke) and mortality risk. Overall, the risk of CVD events was 10% lower for each 10 ng/mL increase in serum 25(OH)D.
Heart
Serum 25-hydroxyvitamin D and the risk of cardiovascular disease: dose-response meta-analysis of prospective studies
The American Journal of Clinical Nutrition
This meta-analysis of 34 observational studies that followed 180,667 participants showed that baseline serum 25(OH)D levels were inversely associated with total number of cardiovascular disease (CVD) events (including myocardial infarction, ischemic heart disease, heart failure, and stroke) and mortality risk. Overall, the risk of CVD events was 10% lower for each 10 ng/mL increase in serum 25(OH)D.
Heart
Low sun exposure habits is associated with a dose‑dependent increased risk of hypertension: a report from the large MISS cohort
Photochemical & Photobiological Sciences
This observational study involving 23,593 women found that sun exposure was associated with a dose-dependent reduced risk of hypertension, which might partly explain the fewer deaths of cardiovascular disease with increasing sun exposure. As compared to those women with the greatest sun exposure, women with low and moderate sun exposure were at 41% and 15% higher odds of hypertension.
Heart
Low sun exposure habits is associated with a dose‑dependent increased risk of hypertension: a report from the large MISS cohort
Photochemical & Photobiological Sciences
This observational study involving 23,593 women found that sun exposure was associated with a dose-dependent reduced risk of hypertension, which might partly explain the fewer deaths of cardiovascular disease with increasing sun exposure. As compared to those women with the greatest sun exposure, women with low and moderate sun exposure were at 41% and 15% higher odds of hypertension.