Clinical Research
The health effects of sunlight are supported by decades of research - Solius is built on that science.
See the studies - click to filter by category
Better wellness & longevity
Evidence suggests that UVB light, like the Solius spectrum, may support the internal systems linked to longer healthspan, including immunity, cognition, cardiovascular function, and metabolic balance.
Potential benefits
System-level support for immunity, brain health, cardiovascular function, and metabolism.
Light-activated molecules that help promote long-term vitality and resilience.
Research associations linking sunlight pathways to improved markers of healthy aging.
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Better wellness & longevity
Evidence suggests that UVB light, like the Solius spectrum, may support the internal systems linked to longer healthspan, including immunity, cognition, cardiovascular function, and metabolic balance.
Potential benefits
System-level support for immunity, brain health, cardiovascular function, and metabolism.
Light-activated molecules that help promote long-term vitality and resilience.
Research associations linking sunlight pathways to improved markers of healthy aging.
See More
Better wellness & longevity
Evidence suggests that UVB light, like the Solius spectrum, may support the internal systems linked to longer healthspan, including immunity, cognition, cardiovascular function, and metabolic balance.
Potential benefits
System-level support for immunity, brain health, cardiovascular function, and metabolism.
Light-activated molecules that help promote long-term vitality and resilience.
Research associations linking sunlight pathways to improved markers of healthy aging.
See More
This review article discusses the gut microbiota and vitamin D as an emerging and vital axis influencing immune aging and age-related diseases. It highlights the dual role of gut microbiota in shaping host immunity and regulating vitamin D metabolism, alongside the significant immunomodulatory potential of vitamin D in maintaining intestinal homeostasis and barrier integrity. The findings suggest that vitamin D deficiency and gut dysbiosis accelerate immunosenescence and inflammageing, contributing to unhealthy aging and increased risk of age-related diseases.
Gut-vitamin D interplay: key to mitigating immunosenescence and promoting healthy ageing
Immunity & Ageing
This review article discusses the gut microbiota and vitamin D as an emerging and vital axis influencing immune aging and age-related diseases. It highlights the dual role of gut microbiota in shaping host immunity and regulating vitamin D metabolism, alongside the significant immunomodulatory potential of vitamin D in maintaining intestinal homeostasis and barrier integrity. The findings suggest that vitamin D deficiency and gut dysbiosis accelerate immunosenescence and inflammageing, contributing to unhealthy aging and increased risk of age-related diseases.
This review article discusses the gut microbiota and vitamin D as an emerging and vital axis influencing immune aging and age-related diseases. It highlights the dual role of gut microbiota in shaping host immunity and regulating vitamin D metabolism, alongside the significant immunomodulatory potential of vitamin D in maintaining intestinal homeostasis and barrier integrity. The findings suggest that vitamin D deficiency and gut dysbiosis accelerate immunosenescence and inflammageing, contributing to unhealthy aging and increased risk of age-related diseases.
This analysis of data from almost 30,000 women from the Melanoma in Southern Sweden (MISS) cohort found that nonsmokers who avoided sun exposure had a life expectancy similar to smokers in the highest sun exposure group, indicating that avoidance of sun exposure is a risk factor for death of a similar magnitude as smoking. Moreover, compared to women with the highest sun exposure, life expectancy for women who avoided the sun was shorter by up to 2.1 years.
Avoidance of sun exposure is a risk factor for all-cause mortality: results from the Melanoma in Southern Sweden cohort
Journal of Internal Medicine
This analysis of data from almost 30,000 women from the Melanoma in Southern Sweden (MISS) cohort found that nonsmokers who avoided sun exposure had a life expectancy similar to smokers in the highest sun exposure group, indicating that avoidance of sun exposure is a risk factor for death of a similar magnitude as smoking. Moreover, compared to women with the highest sun exposure, life expectancy for women who avoided the sun was shorter by up to 2.1 years.
This analysis of data from almost 30,000 women from the Melanoma in Southern Sweden (MISS) cohort found that nonsmokers who avoided sun exposure had a life expectancy similar to smokers in the highest sun exposure group, indicating that avoidance of sun exposure is a risk factor for death of a similar magnitude as smoking. Moreover, compared to women with the highest sun exposure, life expectancy for women who avoided the sun was shorter by up to 2.1 years.
International Journal of Environmental Research and Public Health
This study suggests that 820,000 deaths per year in the United States and Europe and an increased incidence of breast cancer, colorectal cancer, hypertension, cardiovascular disease, metabolic syndrome, multiple sclerosis, Alzheimer's disease, autism, asthma, type 1 diabetes, and myopia could be attributed to insufficient sun exposure.
Insufficient Sun Exposure Has Become a Real Public Health Problem
International Journal of Environmental Research and Public Health
This study suggests that 820,000 deaths per year in the United States and Europe and an increased incidence of breast cancer, colorectal cancer, hypertension, cardiovascular disease, metabolic syndrome, multiple sclerosis, Alzheimer's disease, autism, asthma, type 1 diabetes, and myopia could be attributed to insufficient sun exposure.
International Journal of Environmental Research and Public Health
This study suggests that 820,000 deaths per year in the United States and Europe and an increased incidence of breast cancer, colorectal cancer, hypertension, cardiovascular disease, metabolic syndrome, multiple sclerosis, Alzheimer's disease, autism, asthma, type 1 diabetes, and myopia could be attributed to insufficient sun exposure.
Photochemical & Photobiological Sciences
This review article, assembled by a team of UV experts, indicates that UV exposure may support multiple internal systems linked to a longer healthspan, including immune regulation, cardiovascular health, metabolic balance, and neuro-endocrine function. UV exposure activates complex neuro-immune-endocrine pathways through the skin that influence systemic physiology. These effects include lowering blood pressure via nitric oxide release, modulating inflammatory and immune responses, supporting metabolic processes related to weight, glucose homeostasis, and adipose tissue function, and influencing hormonal and reproductive pathways. Large cohort studies also associate higher lifetime sunlight exposure with reduced all-cause and cardiovascular mortality, suggesting that sunlight-induced UV signaling may contribute to enhanced longevity and reduced risk of cardiometabolic and inflammatory diseases.
Beneficial health effects of ultraviolet radiation: expert review and conference report
Photochemical & Photobiological Sciences
This review article, assembled by a team of UV experts, indicates that UV exposure may support multiple internal systems linked to a longer healthspan, including immune regulation, cardiovascular health, metabolic balance, and neuro-endocrine function. UV exposure activates complex neuro-immune-endocrine pathways through the skin that influence systemic physiology. These effects include lowering blood pressure via nitric oxide release, modulating inflammatory and immune responses, supporting metabolic processes related to weight, glucose homeostasis, and adipose tissue function, and influencing hormonal and reproductive pathways. Large cohort studies also associate higher lifetime sunlight exposure with reduced all-cause and cardiovascular mortality, suggesting that sunlight-induced UV signaling may contribute to enhanced longevity and reduced risk of cardiometabolic and inflammatory diseases.
Photochemical & Photobiological Sciences
This review article, assembled by a team of UV experts, indicates that UV exposure may support multiple internal systems linked to a longer healthspan, including immune regulation, cardiovascular health, metabolic balance, and neuro-endocrine function. UV exposure activates complex neuro-immune-endocrine pathways through the skin that influence systemic physiology. These effects include lowering blood pressure via nitric oxide release, modulating inflammatory and immune responses, supporting metabolic processes related to weight, glucose homeostasis, and adipose tissue function, and influencing hormonal and reproductive pathways. Large cohort studies also associate higher lifetime sunlight exposure with reduced all-cause and cardiovascular mortality, suggesting that sunlight-induced UV signaling may contribute to enhanced longevity and reduced risk of cardiometabolic and inflammatory diseases.
Wellness & Longevity
Health & Place
In this study that looked at UV light exposure and mortality data for over 500,000 individuals, UV exposure was inversely associated with all-cause, cardiovascular disease (CVD) and cancer mortality. Solarium users were also at a lower risk of non-CVD and non-cancer mortality.
Wellness & Longevity
Health & Place
In this study that looked at UV light exposure and mortality data for over 500,000 individuals, UV exposure was inversely associated with all-cause, cardiovascular disease (CVD) and cancer mortality. Solarium users were also at a lower risk of non-CVD and non-cancer mortality.
Wellness & Longevity
The American Journal of Clinical Nutrition
Analysis of data from the VITAL trial found that 4-years of supplementation with 2000 IU/day vitamin D3 reduced telomere attrition by 140 bp, suggesting that vitamin D3 daily supplementation might have a role in counteracting telomere erosion or cell senescence.
Wellness & Longevity
The American Journal of Clinical Nutrition
Analysis of data from the VITAL trial found that 4-years of supplementation with 2000 IU/day vitamin D3 reduced telomere attrition by 140 bp, suggesting that vitamin D3 daily supplementation might have a role in counteracting telomere erosion or cell senescence.
Wellness & Longevity
Endocrine Practice
This paper by vitamin D expert Dr. Holick compares the 2024 and 2011 Endocrine Society Clinical Practice Guidelines on vitamin D and explains why concentrations of 25-hydroxyvitamin D should be at least 30 ng/mL with a preferred range of 40-60 ng/mL as recommended by the 2011 Guidelines in order to obtain maximum extra skeletal benefits from vitamin D including reducing risk of upper respiratory tract infection for children and adults, autoimmune disorders, pre-eclampsia, low birth weight, neonatal dental caries, and deadly cancers.
Wellness & Longevity
Endocrine Practice
This paper by vitamin D expert Dr. Holick compares the 2024 and 2011 Endocrine Society Clinical Practice Guidelines on vitamin D and explains why concentrations of 25-hydroxyvitamin D should be at least 30 ng/mL with a preferred range of 40-60 ng/mL as recommended by the 2011 Guidelines in order to obtain maximum extra skeletal benefits from vitamin D including reducing risk of upper respiratory tract infection for children and adults, autoimmune disorders, pre-eclampsia, low birth weight, neonatal dental caries, and deadly cancers.
Wellness & Longevity
Journal of Investigative Dermatology
This review article by ultraviolet expert Richard Weller highlights that while ultraviolet radiation is a known as a skin carcinogen, many studies correlate sun exposure with reduced all-cause, cardiovascular, and cancer mortality. The paper suggests that sunlight may confer health benefits beyond vitamin D synthesis, such as the photomobilization of nitric oxide from skin stores, which can reduce cardiovascular morbidity.
Wellness & Longevity
Journal of Investigative Dermatology
This review article by ultraviolet expert Richard Weller highlights that while ultraviolet radiation is a known as a skin carcinogen, many studies correlate sun exposure with reduced all-cause, cardiovascular, and cancer mortality. The paper suggests that sunlight may confer health benefits beyond vitamin D synthesis, such as the photomobilization of nitric oxide from skin stores, which can reduce cardiovascular morbidity.
Wellness & Longevity
Nutrients
This systematic review of 289 articles concluded that data strongly suggested that maintaining serum vitamin D concentrations of more than 50 ng/mL is associated with significant risk reduction from viral and bacterial infections, sepsis, and autoimmunity.
Wellness & Longevity
Nutrients
This systematic review of 289 articles concluded that data strongly suggested that maintaining serum vitamin D concentrations of more than 50 ng/mL is associated with significant risk reduction from viral and bacterial infections, sepsis, and autoimmunity.
Wellness & Longevity
Dermato-Endocrinology
The article discusses the benefits of UV light independent of vitamin D supplementation, including increased production of nitric oxide which reduces blood pressure and generally improves cardiovascular health, protective effects of increased melanin in the skin which can act as a sunscreen, suppressed symptoms from multiple sclerosis, improved mood and energy through released endorphins, and improved immunity through modulation of various cytokines and enzymes.
Wellness & Longevity
Dermato-Endocrinology
The article discusses the benefits of UV light independent of vitamin D supplementation, including increased production of nitric oxide which reduces blood pressure and generally improves cardiovascular health, protective effects of increased melanin in the skin which can act as a sunscreen, suppressed symptoms from multiple sclerosis, improved mood and energy through released endorphins, and improved immunity through modulation of various cytokines and enzymes.
Wellness & Longevity
Annals of the New York Academy of Sciences
This report summarizes research on the roles for vitamin D in cancer, immunity and autoimmune diseases, cardiovascular and respiratory health, pregnancy, obesity, erythropoiesis, diabetes, muscle function, and aging.
Wellness & Longevity
Annals of the New York Academy of Sciences
This report summarizes research on the roles for vitamin D in cancer, immunity and autoimmune diseases, cardiovascular and respiratory health, pregnancy, obesity, erythropoiesis, diabetes, muscle function, and aging.
Wellness & Longevity
Nutrients
Solar UV has been inversely correlated with geographical and seasonal variation in many health conditions, including cardiovascular disease and respiratory infections. This article discusses how this effect could be impacted by various factors, including nitric oxide production, heat, vitamin D, and gene expression. The author, vitamin D expert William Grant, recommend increasing exposure to summer sunlight without sunburn to improve health.
Wellness & Longevity
Nutrients
Solar UV has been inversely correlated with geographical and seasonal variation in many health conditions, including cardiovascular disease and respiratory infections. This article discusses how this effect could be impacted by various factors, including nitric oxide production, heat, vitamin D, and gene expression. The author, vitamin D expert William Grant, recommend increasing exposure to summer sunlight without sunburn to improve health.
